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Development of an Experimental Model for Spontaneous Lymph Node Metastasis of Human Esophageal Carcinoma in Nude Mice—Histopathological Analysis

  • Hiroshi Yoshimura
  • Akira Shigetomi
  • Tsukasa Kotoh
  • Kenji Suzuki
  • Dipok Kumar Dhar
  • Hiroshi Matsuura
  • Teruhisa Nakamura
  • Takeyuki Harada
  • Shigeru Morikawa
Conference paper

Abstract

Metastasis, a unique feature of malignant neoplasms, is the major cause of death among cancer patients. The exact mechanisms responsible for metastases are not fully understood because of the lack of proper experimental models. We established a new experimental model of spontaneous lymph node metastasis of human esophageal carcinoma in nude mice and analyzed the mode of metastasis formation histopathologically.

Keywords

Esophageal Cancer Nude Mouse Esophageal Carcinoma Popliteal Lymph Node Squamous Cell Carcinoma Cell Line 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Tokyo 1993

Authors and Affiliations

  • Hiroshi Yoshimura
  • Akira Shigetomi
  • Tsukasa Kotoh
  • Kenji Suzuki
  • Dipok Kumar Dhar
  • Hiroshi Matsuura
  • Teruhisa Nakamura
    • 1
  • Takeyuki Harada
  • Shigeru Morikawa
    • 2
  1. 1.Second Department of SurgeryShimane Medical UniversityIzumo, Shimane, 693Japan
  2. 2.First Department of PathologyShimane Medical UniversityIzumo, Shimane, 693Japan

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