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Analysis of Gene Amplification in Human Esophageal Cancer

  • Hiroyuki Suzuki
  • Shichisaburo Abo
  • Michihiko Kitamura
  • Masaji Hashimoto
  • Keiichi Izumi
  • Kunihiko Terada
  • Toshihiro Sugiyama

Abstract

The “multistep” of genetic alterations is necessary for cancer formation [1], but there are few reports dealing with both oncogenes and tumor suppressor genes in human esophageal cancer. To investigate the correlation between oncogenes and esophageal cancer, we examined gene amplification of the int-2 and erbB genes, and the p53 and DCC tumor suppressor genes by Southern blot analysis.

Keywords

Esophageal Cancer Southern Blot Analysis Esophageal Carcinoma Epidermal Growth Factor Receptor Gene erbB Gene 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Tokyo 1993

Authors and Affiliations

  • Hiroyuki Suzuki
    • 1
  • Shichisaburo Abo
    • 1
  • Michihiko Kitamura
    • 1
  • Masaji Hashimoto
    • 1
  • Keiichi Izumi
    • 1
  • Kunihiko Terada
    • 2
  • Toshihiro Sugiyama
    • 2
  1. 1.Second Department of SurgeryAkita University School of MedicineAkita, 010Japan
  2. 2.Department of BiochemistryAkita University School of MedicineAkita, 010Japan

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