Abstract
In esophageal carcinoma, amplification of epidermal growth factor receptor and c-myc gene [1], and coamplification of hst-1 and int-2 genes [2, 3] have been reported. The incidence of coamplification of the hst-1 and int-2 genes was reported at 30%–50% and was correlated with poor prognosis and high incidence of postoperative recurrence in distal organs of esophageal carcinoma [4]. In this study, we examined whether or not the intensity of hst-1 amplification is associated with the grade of malignant potential, especially organ metastasis, of esophageal carcinoma.
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References
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© 1993 Springer-Verlag Tokyo
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Chikuba, K. et al. (1993). Association of hst-1 Gene Amplification with Poor Postoperative Prognosis of Esophageal Carcinoma. In: Nabeya, Ki., Hanaoka, T., Nogami, H. (eds) Recent Advances in Diseases of the Esophagus. Springer, Tokyo. https://doi.org/10.1007/978-4-431-68246-2_71
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DOI: https://doi.org/10.1007/978-4-431-68246-2_71
Publisher Name: Springer, Tokyo
Print ISBN: 978-4-431-68248-6
Online ISBN: 978-4-431-68246-2
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