Recombinant Human Growth Hormone Improves Postoperative Protein Retention of Patients Receiving Esophagectomy

  • Tsuguhiko Tashiro
  • Kazuya Takagi
  • Yoshiya Mashima
  • Hideo Yamamori
  • Masahiko Nishizawa
  • Nobuyuki Nakajima
Conference paper


Surgical treatment for esophageal cancer, which includes thoracotomy, laparotomy, and three-field lymph node dissection [1] followed by reconstruction, is one of the most severe operative procedures resulting in an increased protein catabolism with supressed immune function. Growth hormone has a strong anabolic effect and became applicable for clinical use owing to the availability of recombinant human growth hormone (rhGH) by the development of bioengineering techniques. The effects of rhGH in the stressed state were investigated experimentally and clinically.


Growth Hormone Total Parenteral Nutrition Human Growth Hormone Nitrogen Balance Recombinant Human Growth Hormone 
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Copyright information

© Springer-Verlag Tokyo 1993

Authors and Affiliations

  • Tsuguhiko Tashiro
  • Kazuya Takagi
  • Yoshiya Mashima
  • Hideo Yamamori
  • Masahiko Nishizawa
  • Nobuyuki Nakajima
    • 1
  1. 1.The First Department of SurgeryChiba University Medical SchoolChuo-ku, Chiba, 260Japan

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