Advertisement

Quality of Life After Laser Therapy in Patients with Inoperable Cancer of the Esophagus and Gastric Cardia

  • A. Moraldi
  • P. Ginevri
  • C. Iascone
  • S. Stipa
  • C. U. Casciani
Conference paper

Abstract

Many patients with carcinoma of the esophagus and gastric cardia, when first seen, are inoperable either because of advanced disease or extremely poor general condition. Then the only therapeutic goal in these patients is palliation of dysphagia, to improve their quality of life until death occurs from cachexia, metastatic disease, or cardio-respiratory insufficiency. Resolution of malignant dysphagia with recanalization of the esophagus and gastric cardia by endoscopic Nd:YAG (neodymium: yttrium-aluminum-garnet) laser photocoagulation was introduced in the early 1980s; since that time many patients have been successfully treated because the method has been accepted more and more in the last few years. In fact, laser therapy has some characteristics such as ease of performance, short or no hospitalization, low morbidity and practically no mortality, which are indispensable for a treatment that is only palliative and for patients with a life expectancy that is usually less than 6 months.

Keywords

Laser Treatment Laser Therapy Gastric Cardia Poor General Condition Anastomotic Recurrence 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Naveau S, Chiesa A, Poynard T, Chapt JC (1990) Endoscopic Nd: YAG laser therapy as palliative treatment for esophageal and cardial cancer. Dig Dis Sci 35: 295–301Google Scholar
  2. 2.
    Stange EF, Dylla J, Fleig WE (1989) Laser treatment of upper gastrointestinal tract carcinoma: Determinants of survival. Endoscopy 21: 254–257PubMedCrossRefGoogle Scholar
  3. 3.
    Siegel HI, Laskin KJ, Dabezies MA, Fisher RS, Krevsky B (1991) The effect of endoscopic laser therapy on survival in patients with squamous cell carcinoma of the esophagus. J Clin Gastroenterol 13: 142–146PubMedCrossRefGoogle Scholar
  4. 4.
    Loizou LA, Grigg D, Atkinson M, Robertson C, Bown SG (1991) A prospective com–parison of laser therapy and intubation in endoscopic palliation for malignant dysphagia. Gastroenterology 100: 1303–1310PubMedGoogle Scholar
  5. 5.
    Hahl J, Salo J, Ovaska J, Haapiainen R, Kalima T, Schroder T (1991) Comparison of endoscopic Nd:YAG laser therapy and esophageal tube in palliation of esophagogastric malignancy. Scand J Gastroenterol 26: 103–108PubMedCrossRefGoogle Scholar
  6. 6.
    Barr H, Krasner N, Raoul A, Walker RJ (1990) Prospective randomized trial of laser therapy only and laser therapy followed by endoscopic intubation for the palliation of malignant dysphagia. Gut 31: 252–258PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag Tokyo 1993

Authors and Affiliations

  • A. Moraldi
    • 1
  • P. Ginevri
    • 1
  • C. Iascone
    • 2
  • S. Stipa
    • 2
  • C. U. Casciani
    • 1
  1. 1.Clinica ChirurgicaUniversità degli Studi di Roma “Tor Vergata”RomeItaly
  2. 2.Istituto di 1^ Clinica ChirurgicaUniversità degli Studi di Roma “La Sapienza”RomeItaly

Personalised recommendations