Abstract
The prognosis of patients with advanced cancer of the esophagus is very poor. To control advanced esophageal carcinoma nonoperatively, irradiation and chemotherapy have been applied. However, the clinical effectiveness of these treatments has not been satisfactory. Hyperthermia has recently received attention since neoplastic cells have been reported to have greater heat-sensitivity than normal cells, and because this method has been confirmed to enhance the anticancer effect of radiation and some anticancer drugs. We have employed multidisciplinary treatment consisting of radiotherapy, chemotherapy, and hyperthermia, since 1985 [1]. This treatment protocol was derived from basic experiments using cultured cells of human cancer of the esophagus. This is a report of our study on the efficacy of hyperthermia in combined treatment.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Fujimaki M, Katoh H, Tazawa K, Yamashita I, Sakamoto T, Yamada A (1990) Adjuvant hyperthermia in nonresectable esophageal carcinoma. In: Ferguson MK, Little AG, Skinner DB (eds) Disease of the esophagus, vol. 1: Malignant diseases. Fut 317–322
Japanese Society for Esophageal Diseases (1992) Guidelines for the cli studies on carcinoma of the esophagus. Kanehara, Tokyo, pp 32–58
Shinbo T, Katoh H, Saitoh M, Saitoh T, Shimizu T, Otagiri H, (1989) Effect of thermotherapy on human esophageal carcinoma in cases. Gan to Kagaku Ryoho (Jpn J Cancer Chemother) 16 (4): 1899–1904
Sugimachi K, Inokuchi K, Kai H, Sogawa A, Kawai Y (1983) En application of hyperthermia to malignant lesions. Jpn J Cancer Res (Gann) 74: 622–624
Sugimachi K, Kai H, Matsufuji H, Ueo H, Inokuchi K (1986) Histopthological evaluation of hyperthermo-chemo-radiotherapy for carcinoma of the esophagus. J Surg Oncol 32: 82–85
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1993 Springer-Verlag Tokyo
About this paper
Cite this paper
Shimizu, T. et al. (1993). Efficacy of Hyperthermia for Advanced Esophageal Carcinoma. In: Nabeya, Ki., Hanaoka, T., Nogami, H. (eds) Recent Advances in Diseases of the Esophagus. Springer, Tokyo. https://doi.org/10.1007/978-4-431-68246-2_161
Download citation
DOI: https://doi.org/10.1007/978-4-431-68246-2_161
Publisher Name: Springer, Tokyo
Print ISBN: 978-4-431-68248-6
Online ISBN: 978-4-431-68246-2
eBook Packages: Springer Book Archive