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Efficacy of Hyperthermia for Advanced Esophageal Carcinoma

  • Tetsuro Shimizu
  • Hiroshi Kato
  • Shigeru Takemori
  • Masahiro Okamoto
  • Tomohiro Saito
  • Iwao Yamashita
  • Akira Yamada
  • Takashi Sakamoto
  • Yoshiaki Karaki
  • Kenji Tazawa
  • Masao Fujimaki
Conference paper

Abstract

The prognosis of patients with advanced cancer of the esophagus is very poor. To control advanced esophageal carcinoma nonoperatively, irradiation and chemotherapy have been applied. However, the clinical effectiveness of these treatments has not been satisfactory. Hyperthermia has recently received attention since neoplastic cells have been reported to have greater heat-sensitivity than normal cells, and because this method has been confirmed to enhance the anticancer effect of radiation and some anticancer drugs. We have employed multidisciplinary treatment consisting of radiotherapy, chemotherapy, and hyperthermia, since 1985 [1]. This treatment protocol was derived from basic experiments using cultured cells of human cancer of the esophagus. This is a report of our study on the efficacy of hyperthermia in combined treatment.

Keywords

Esophageal Cancer Pulmonary Fibrosis Esophageal Carcinoma Small Cell Carcinoma Multidisciplinary Treatment 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

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Copyright information

© Springer-Verlag Tokyo 1993

Authors and Affiliations

  • Tetsuro Shimizu
  • Hiroshi Kato
  • Shigeru Takemori
  • Masahiro Okamoto
  • Tomohiro Saito
  • Iwao Yamashita
  • Akira Yamada
  • Takashi Sakamoto
  • Yoshiaki Karaki
  • Kenji Tazawa
  • Masao Fujimaki
    • 1
  1. 1.The Second Department of Surgery, Faculty of MedicineToyama Medical and Pharmaceutical UniversityToyama City, ToyamaJapan

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