Advertisement

Postoperative Irradiation for Esophageal Carcinoma

  • Shogo Yamada
  • Yoshihiro Takai
  • Kenji Nemoto
  • Yoshihisa Kakuto
  • Yoshihiro Ogawa
  • Akihiko Hoshi
  • Kiyohiko Sakamoto
  • Tetsuro Nishihira
  • Shozo Mori
Conference paper

Abstract

Postoperative irradiation for curative resection of esophageal carcinoma has been used in order to eradicate micro-dissemination and micro-metastases. Generally, a long T-shaped field is employed for postoperative irradiation, and the risk of radiation myelopathy increases even at low doses when the irradiated volume of the spinal cord enlarges. Some questions arise about the postoperative irradiation: First, whether its effectiveness outweighs the risk; second, for which patients it is indispensable; third, what is the optimal dose of irradiation; fourth, whether combined chemotherapy improves the prognosis; and fifth, what the actual incidence of radiation myelopathy is. We analyzed data compiled over the last decade.

Keywords

Esophageal Carcinoma Postoperative Irradiation Radiation Myelopathy Male And28 Female Dose Preoperative Radiotherapy 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Cox DR (1972) Regression models and life tables. J Royal Stat Soc Series B 34: 187–220Google Scholar
  2. 2.
    Launois B, Delarue D, Campion JP, Kerbaol M (1981) Preoperative radiotherapy for carcinoma of the esophagus. Surg Gynecol Obst 153: 690–692Google Scholar
  3. 3.
    Sugimachi K, Kitamura M, Inokuchi K, Ohsato K, Yoshimatsu H, Matsuura K, Inuzuka S, Ono Y, Furusawa M, Hata K, Kakegawa T, Ohtake H, Tomita M, Honbo Z, Kobayashi M, Shirabe J, Ashizawa A, Miyauchi Y, Akagi M, Takahashi M, Koga Y, Watanabe K (1986) Clinical results of esophageal cancer in Kyushu district—Analysis of 2126 cases. J Jpn Soc Cancer Ther 21: 1423–1432Google Scholar
  4. 4.
    Mei W, Xian-Zhi G, Weibo Y, Guojun H, Liang-Jun W, Da-Wei Z (1989) Randomized clinical trial on the combination of preoperative irradiation and surgery in the treatment of esophageal carcinoma: Report on 206 patients. Int J Radiat Oncol Biol Phys 16: 325–327CrossRefGoogle Scholar
  5. 5.
    Arnott SJ, Duncan W, Kerr GR, Walbaum PR, Cameron E, Jack WJL, Mackillop WJ (1992) Low dose preoperative radiotherapy for carcinoma of the esophagus: Results of a randomized clinical trial. Radiother Oncol 24: 108–113PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag Tokyo 1993

Authors and Affiliations

  • Shogo Yamada
  • Yoshihiro Takai
  • Kenji Nemoto
  • Yoshihisa Kakuto
  • Yoshihiro Ogawa
  • Akihiko Hoshi
  • Kiyohiko Sakamoto
    • 1
  • Tetsuro Nishihira
  • Shozo Mori
    • 2
  1. 1.Department of RadiologyTohoku University School of MedicineAoba-ku, Sendai, 980Japan
  2. 2.Second Department of SurgeryTohoku University School of MedicineAoba-ku, Sendai, 980Japan

Personalised recommendations