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Preoperative Concurrent Chemotherapy and Radiotherapy of Squamous Cell Carcinoma of the Thoracic Esophagus: A Pilot Study Report

  • Andrzej W. Szawlowski
  • Slawomir Falkowski
  • Tadeusz Morysinski
  • Anna Nasierowska-Guttmejer
  • Andrzej Karwowski
  • Marek Krawczyk
  • Andrzej Kulakowski
Conference paper

Abstract

In Poland, 1300 new cases of carcinoma of the esophagus are registered each year and it ranges from 1.1 in women to 4.8 in men per 100,000 population [1]. Most of the esophageal cancer patients admitted to the hospitals are in an advanced stage of the disease, and this is mainly responsible for the low operability/resecability rates and therefore poor long-term results of treatment (5-year survival is around 4%, the lowest of all gastro-intestinal cancers). Since no significant progress in early diagnosis has been observed, the attempts to improve the results concentrate on combining other modes of treatment (e.g., radio- and/or chemotherapy) before surgery (Fig. 1). Currently, surgery, whenever possible, remains the treatment of choice for carcinoma of the esophagus aimed at palliation or cure, whether or not it is associated with radiotherapy pre- and/or postoperatively. The place and the role of chemotherapy (combined or monotherapy) in the treatment program for esophageal carcinoma is still unproven, and is under evaluation for its potential benefits by ongoing prospective clinical trials.

Keywords

Squamous Cell Carcinoma Clin Oncol Concurrent Chemotherapy Thoracic Esophagus Esophageal Cancer Patient 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Tokyo 1993

Authors and Affiliations

  • Andrzej W. Szawlowski
    • 1
  • Slawomir Falkowski
    • 2
  • Tadeusz Morysinski
    • 3
  • Anna Nasierowska-Guttmejer
    • 4
  • Andrzej Karwowski
    • 5
  • Marek Krawczyk
    • 5
  • Andrzej Kulakowski
    • 1
  1. 1.Department of Surgical OncologyThe Maria Sklodowska-Curie Memorial Cancer Center and Institute of OncologyWarsawPoland
  2. 2.Department of ChemotherapyThe Maria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology00-973 WarsawPoland
  3. 3.Department of RadiotherapyThe Maria Sklodowska-Curie Memorial Cancer Center and Institute of OncologyWarsawPoland
  4. 4.Department of Tumour PathologyThe Maria Sklodowska-Curie Memorial Cancer Center and Institute of OncologyWarsawPoland
  5. 5.Department of General and Hepatic SurgeryMedical AcademyWarsawPoland

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