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Drug Sensitivity Tests for Human Esophageal Cancer

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Recent Advances in Diseases of the Esophagus

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Abstract

Recently, considerable attention has been paid to the study of systemic chemo-therapy with esophageal cancer. Although relatively good response rates have been obtained compared with other gastrointestinal tumors [1], the prognosis is still worse than for other type of gastrointestinal tumors because of the poor general condition in many patients and the rapidity of tumor progression. To improve the response rate to chemotherapy and prognosis of these patients, the selection of chemotherapeutic agent is very important. The present study was designed to evaluate and compare the usefulness of in vitro human tumor clonogenic assay (HTCA), in vivo subrenal capsule assay (SRCA), SRCA with immunosuppressant (IS-SRCA) and in vitro adenosine triphosphate (ATP) assay with serum-free culture (SF-ATPA) as chemosensitivity tests in human esophageal squamous cell carcinoma.

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References

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Author information

Authors and Affiliations

  1. Department of Surgery 1, Iwate Medical University, School of Medicine, 19-1 Uchimaru, Morioka, Iwate, 020, Japan

    K. Saito

Authors
  1. M. Terashima
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  2. K. Ikeda
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  3. H. Kawamura
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  4. C. Maesawa
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  5. H. Yoshinari
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  6. K. Koeda
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  7. N. Sato
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  8. K. Ishida
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  9. K. Saito
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Editor information

Editors and Affiliations

  1. Second Department of Surgery, Kyorin University School of Medicine, 6-20-2, Shinkawa, Mitaka, Tokyo, 181, Japan

    Kin-ichi Nabeya M.D. , Tateo Hanaoka M.D.  & Hiroshi Nogami M.D. ,  & 

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© 1993 Springer-Verlag Tokyo

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Terashima, M. et al. (1993). Drug Sensitivity Tests for Human Esophageal Cancer. In: Nabeya, Ki., Hanaoka, T., Nogami, H. (eds) Recent Advances in Diseases of the Esophagus. Springer, Tokyo. https://doi.org/10.1007/978-4-431-68246-2_149

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  • DOI: https://doi.org/10.1007/978-4-431-68246-2_149

  • Publisher Name: Springer, Tokyo

  • Print ISBN: 978-4-431-68248-6

  • Online ISBN: 978-4-431-68246-2

  • eBook Packages: Springer Book Archive

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