The Impact of Close Surveillance of Barrett’s Esophagus Patients on the Results of Esophagogastrectomy for Carcinoma

  • John M. StreitzJr.
  • F. Henry EllisJr.
  • Charles AndrewsJr.


The risk of malignant degeneration in patients with Barrett’s esophagus (BE) is well known. However, the potential benefits of close surveillance of such patients in terms of the early detection of cancer and the results of esophagogastrectomy following its early detection remain poorly documented. This study was undertaken to determine whether or not there are clearly identifiable benefits from close surveillance of patients with benign BE.


Invasive Carcinoma High Grade Dysplasia Endoscopic Surveillance Close Surveillance Surveillance Interval 
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  1. 1.
    Streitz JM, Jr, Ellis FH Jr, Gibb SP (1991) Adenocarcioma in Barrett’s esophagus: A clinicopathologic study of 65 cases. Ann Surg 213: 122–125PubMedCrossRefGoogle Scholar
  2. 2.
    Streitz JM Jr, Andrews CW Jr, Ellis FH Jr (to be published) Endoscopic surveillance of Barrett’s esophagus. Does it help? J Thorac Cardiovasc SurgGoogle Scholar
  3. 3.
    Schmidt HG, Riddell RH, Walther B, et al (1985) Dysplasia in Barrett’s esophagus. J Cancer Res Clin Oncol 110: 145–152PubMedCrossRefGoogle Scholar
  4. 4.
    Reid BJ, Haggitt RC, Rubin CE, et al (1988) Observer variation in the diagnosis of dysplasia in Barrett’s esophagus. Hum Pathol 19: 166–178PubMedCrossRefGoogle Scholar
  5. 5.
    Beahrs OH, Henson DE, Hutter RVP, Myers MH (1988) Manual for staging of cancer, 3rd Edn. JB Lippincott, Philadelphia, pp 63–67Google Scholar
  6. 6.
    Kaplan EL, Meier P (1958) Nonparametric estimation from incomplete observations. J Am Statist Assoc 53: 457–481CrossRefGoogle Scholar
  7. 7.
    Tarone RE, Ware J (1977) On distribution-free tests for equality of survival distributions. Biometrika 64: 156–160CrossRefGoogle Scholar
  8. 8.
    Altkori NK, Sunagawa M, Little AG, Skinner DB (1991) High-grade dysplasia in the columnar-lined esophagus. Am J Surg 161: 97–100CrossRefGoogle Scholar
  9. 9.
    Pera M, Trastek VF, Carpenter HA, Allen MS, et al (1992) Barrett’s esophagus with high- grade dysplasia: An indication for esophagectomy? Ann Thorac Surg 54: 199–204PubMedCrossRefGoogle Scholar
  10. 10.
    Reid BJ, Lewin R, VanDeventer G, et al (1986) Barrett’s esophagus: High-grade dysplasia and intramucosal carcinoma detected by endoscopic biopsy surveillance (abstract). Gastro-enterology 90: 1601Google Scholar
  11. 11.
    Provenzale D, Wong JB, Kemp JA, Arora S (1990) Endoscopic surveillance for Barrett’s esophagus: Can we afford the cost (abstract)? Am J Gastroenterol 85: 1224Google Scholar
  12. 12.
    Hameeteman W, den Hartog Jager FC A, Tio TL, Tytgat GNS (1988) Early adenocarcinoma of the esophagus. In: Siewert JR, Hölscher AH (eds) Diseases of the esophagus. Springer, Berlin Heidelberg New York, pp 554–558Google Scholar
  13. 13.
    DeMeester TR, Attwood SEA, Smyrk TC, Therkildsen DH, et al: Surgical therapy in Barrett’s esophagus. Ann Surg 212: 528–540Google Scholar

Copyright information

© Springer-Verlag Tokyo 1993

Authors and Affiliations

  • John M. StreitzJr.
    • 1
  • F. Henry EllisJr.
    • 2
  • Charles AndrewsJr.
    • 2
  1. 1.Lahey ClinicBurlingtonUSA
  2. 2.The New England Deaconess Hospital—Harvard Medical SchoolBostonUSA

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