pH-Monitoring Patterns of Gastroesophageal Reflux: Differences Between Populations
Esophageal pH measurement was initialy proposed by Tuttle in 1958 . The further evolution of his concept was the basis of the standard acid reflux test (SART), the acid clearance tests, and recently ambulatory 24-hour esophageal pH monitoring. Using the latter method, the amount of acid refluxed to the esophagus can be quantified and related to the time of day when it occurs [2, 3]. Ambulatory 24-hour pH meters (Holter), mimics as closely as possible the normal circadian variation in gastric pH, although having one or two microelectrodes in the esophagus and/or the stomach can alter the physiologic status of the esophagus, lower esophageal sphincter (LES), or the stomach. The fact that individual pH values can vary physiologically throughout the day, as well as from day to day, or it can be influenced by enviromental factors such as elevation above sea level.
KeywordsGastroesophageal Reflux Lower Esophageal Sphincter Reflux Time Longe Episode Bile Duct Disease
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