Development of a Copmputer Controlled Infusion System
Propofol has a favourable pharmacokinetic profile for use as a total intravenous anaesthetic (1) but the use of intravenous agents to maintain anaesthesia requires a different technique compared with standard volatile anaesthetics delivered via calibrated vaporisers. Several regimes have been suggested for suitable propofol infusions to maintain anaesthesia (2,3,4) but these cannot alter accurately the propofol concentration with changing surgical and anaesthetic requirements.
KeywordsTotal Intravenous Anaesthesia Favourable Pharmacokinetic Profile Target Blood Concentration Booij LHDJ Computer Control Infusion
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- 7.Marsh B, White M, Morton N, Kenny GNC. Pharmacokinetic model-driven infusion of propofol in children. British Journal of Anaesthesia, in pressGoogle Scholar