Advertisement

Assessment of the Value of Computerized Propofol Infusion

  • Gavin NC Kenny
  • Iain Taylor
  • Martin White
Conference paper

Abstract

Propofol has a favorable pharmacokinetic profile for total intravenous anaesthesia but the use of intravenous agents for maintenance of anaesthesia requires a different technique compared with volatile anaesthetics delivered via calibrated vaporizers. Several manual infusion schemes have been proposed, based either on the concept of minimum infusion rate [1] or on approximations to computer generated infusion regimens [2].

Keywords

Infusion System Volatile Anaesthetic Artificial Ventilation Control Infusion Total Intravenous Anaesthesia 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

References

  1. 1.
    Richards MJ, Skues MA, Jarvis AP, Prys-Roberts C. Total I.V. anaesthesia with propofol and alfentanil: dose requirements for propofol. British Journal of Anaesthesia 1999; 61: 510PGoogle Scholar
  2. 2.
    Roberts FL, Dixon J, Lewis GTR, Tackley RM, Prys-Roberts C. Induction and maintenance of propofol anaesthesia: a manual infusion scheme. Anaesthesia 1988, 43: (suppl): 14–17PubMedCrossRefGoogle Scholar
  3. 3.
    Gepts E, Camu F, Cockshott I, Douglas E. Disposition of propofol administered as constant rate infusions in humans. Anesthesia and Analgesia 1987 66: 1256–63PubMedCrossRefGoogle Scholar
  4. 4.
    White M, Kenny GNC. Intravenous propofol anaesthesia using a computerized infusion system. Anaesthesia 1990; 45: 204–209PubMedCrossRefGoogle Scholar
  5. 5.
    Kenny GNC, White M. A portable computerized control system for propofol infusion. Anaesthesia 1990,45: 692–693PubMedCrossRefGoogle Scholar
  6. 6.
    Marsh B, White M, Morton N, Kenny GNC. Pharmacokinetic model driven infusion of propofol in children. British Journal of Anaesthesia, in pressGoogle Scholar

Copyright information

© Springer-Verlag Tokyo 1992

Authors and Affiliations

  • Gavin NC Kenny
    • 1
  • Iain Taylor
    • 1
  • Martin White
    • 1
  1. 1.University Department of Anaesthesia Royal InfirmaryGlasgowUK

Personalised recommendations