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A Simulation Analysis for Optimal Plasma Potassium Concentration during Cardiopulmonary Extracorporeal Bypass

  • Yoshifumi Tanaka
  • Miho Nakagawa
  • Satoru Hashimoto
  • Eiichi Chihara
  • Takashi Kinoshita
  • Munetaka Hirose
Conference paper

Summary

A simulation program to predict optimal plasma potassium ion during cardiopulmonary bypass was constructed from a view point of pharmacokinetics. Experimental results of sodium-22 and data of urinary excretion during cardiac surgeries were used in the model. The change of plasma potassium ion concentration, which was obtained from accidental administrations of KCl showed good agreement with this model. The results of this simulation model provide an useful information to infuse KC1 for the supplement in a condition of hypokalemia such as cardiopulmonary bypass.

Keywords

Cardiac Arrest Cardiopulmonary Bypass Diffusion Constant Potassium Concentration Plasma Potassium 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

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    Tanaka, Y., Hashimoto, S., Shigemi, K., Natsuyama, T. and Miyazaki, M.: Analysis of Sodium and Iothalamate Diffusion Kinetics Between Vascular Space and Interstitial Fluid Space. Circulation Control, Vol. 9 195–200, 1988.Google Scholar
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    Guyton, A. C., Taylor, A.E. and Granger, H. J.: Analyses of pressure equilibria in tissue spaces equilibria at tissue surfaces and at membrane pores. In Circulatory Physiology II. W. B. Saunders Company, Philadelphia, 1975.Google Scholar
  3. 3).
    Vaughan, R. S., Lunn, J. N.: Potassium and the anaesthetist: A review. Anaesthesia, Vol. 28, 118–122, 1973.PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag Tokyo 1992

Authors and Affiliations

  • Yoshifumi Tanaka
    • 1
  • Miho Nakagawa
    • 1
  • Satoru Hashimoto
    • 1
  • Eiichi Chihara
    • 1
  • Takashi Kinoshita
    • 1
  • Munetaka Hirose
    • 1
  1. 1.Department of AnesthesiologyKyoto Prefectural University of MedicineKyotoJapan

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