The role of HBV in hepatocellular carcinoma

  • Satoshi Tanaka
  • Nobu Hattori


Hepatocellular carcinoma (HCC) is one of the most common malignancies worldwide. The incidence of HCC is particularly high in Africa [1, 2] and Asia [3-6]. There is apparently strong epidemiological evidence for an important role of hepatitis B virus (HBV) in the pathogenesis of HCC. However, the precise mechanism by which HBV infection might lead to malignant transformation of hepatocytes is still far from clear.


Primary Liver Cancer Liver Cancer Study Group Cirrhotic Case 
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Copyright information

© Springer-Verlag Tokyo 1992

Authors and Affiliations

  • Satoshi Tanaka
    • 1
  • Nobu Hattori
    • 1
  1. 1.Tokyo Metropolitan Komagome HospitalKomagome, Bunkyo-ku TokyoJapan

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