Multidisciplinary treatment for multiple hepatocellular carcinoma

  • Ken Takasaki
  • Atsushi Aruga


Hepatocellular carcinoma (HCC) is one of the most common malignancies in Japan. However, few HCC patients are candidates for curative surgical resection, due to either associated liver cirrhosis or the presence of multiple tumor nodules in the liver. Several modalities have been used to treat HCC patients including transcatheter arterial embolization (TAE), hepatic arterial infusion, ultrasound (US) guided ethanol injection, radiation, immunotherapy, and hyperthermia, but satisfactory clinical results have not yet been obtained. These non-curative patients can be treated with reduction surgery or hepatic arterial infusion therapy using an implantable injection port (IIP). In this chapter, we will discuss our multidisciplinary treatment of unresectable (non-curative) hepatocellular carcinomas, specially targeting Stage IV-a (IM2,3) multiple HCCs as defined in [1].


Transcatheter Arterial Embolization Hepatic Arterial Infusion Multiple HCCs Bilateral Lobe Superior Pancreaticoduodenal Artery 
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Copyright information

© Springer-Verlag Tokyo 1992

Authors and Affiliations

  • Ken Takasaki
    • 1
  • Atsushi Aruga
    • 1
  1. 1.Department of Surgery, Institute of GastroenterologyTokyo Women’s Medical CollegeShinjuku-ku, TokyoJapan

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