Preoperative portal vein embolization for hepatocellular carcinoma

  • Hiroaki Kinoshita
  • Kazuhiro Hirohashi
  • Shoji Kubo


Advances in diagnostic imaging and new surgical techniques have improved the outcome for many patients with hepatocellular carcinoma (HCC). However, in Japan, more than 70% of patients with HCC have cirrhosis of the liver [1], and resection of the liver of such patients is often limited by the cirrhosis. Therefore, nonsurgical treatments such as transcatheter arterial embolization (TAE) or percutaneous ethanol injection therapy have been developed and are used widely as adjuvant therapy. TAE was first used to treat HCC patients by Goldstein et al. [2], who reasoned that most of the blood flow to the tumor is supplied by the hepatic artery. However, according to a study by the Liver Cancer Study Group of Japan [3], TAE is effective against the main tumor, but not against small intrahepatic metastases or tumor thrombi; it is particularly ineffective against tumor thrombi.


Liver Resection Portal Vein Embolization Tumor Thrombus Transcatheter Arterial Embol Portal Branch 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag Tokyo 1992

Authors and Affiliations

  • Hiroaki Kinoshita
    • 1
  • Kazuhiro Hirohashi
    • 1
  • Shoji Kubo
    • 1
  1. 1.Second Department of SurgeryOsaka City University Medical SchoolAbeno-ku, OsakaJapan

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