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Arterial infusion therapy: Lipiodol-cytostatics with and without embolization

  • Yoshiyuki Shimamura
  • Masanori Ishii
  • Masato Ono
  • Fujio Makita
  • Ryuzo Sekiguchi
  • Masahiro Yoshino
  • Peter Gunvén
  • Kaoru Abe

Abstract

The liver has a dual blood supply by the arterial and portal systems. Primary and secondary liver tumors are mainly nourished arterially, as first suggested by Breedis and Young [1]. This knowledge has guided numerous attempts to affect the growth of liver tumors by reduction of the nutritive arterial flow and/or addition to it of antitumor agents. In both cases, some selectivity of action is expected because the normal liver is to a great extent also supplied by the portal venous flow. The regional infusion of toxic agents could be expected to give diminished side effects as compared to systemic treatment because the agents may be more or less cleared or modified by passage through the liver.

Keywords

Chronic Active Hepatitis Gelatin Sponge Arterial Blood Flow Gastroduodenal Artery Left Hepatic Artery 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Tokyo 1992

Authors and Affiliations

  • Yoshiyuki Shimamura
    • 1
  • Masanori Ishii
    • 1
  • Masato Ono
    • 1
  • Fujio Makita
    • 1
  • Ryuzo Sekiguchi
    • 1
  • Masahiro Yoshino
    • 1
  • Peter Gunvén
    • 1
  • Kaoru Abe
    • 1
  1. 1.National Matsudo HospitalChibaJapan

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