Arterial infusion therapy: Lipiodol-cytostatics with and without embolization
The liver has a dual blood supply by the arterial and portal systems. Primary and secondary liver tumors are mainly nourished arterially, as first suggested by Breedis and Young . This knowledge has guided numerous attempts to affect the growth of liver tumors by reduction of the nutritive arterial flow and/or addition to it of antitumor agents. In both cases, some selectivity of action is expected because the normal liver is to a great extent also supplied by the portal venous flow. The regional infusion of toxic agents could be expected to give diminished side effects as compared to systemic treatment because the agents may be more or less cleared or modified by passage through the liver.
KeywordsChronic Active Hepatitis Gelatin Sponge Arterial Blood Flow Gastroduodenal Artery Left Hepatic Artery
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