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The LEC Rat pp 70-80 | Cite as

Investigation of Infectious Agents Causing Spontaneous Hepatitis in LEC Rats

  • Tsutomu Namieno
  • Noritoshi Takeichi
  • Motomichi Sasaki
  • Kimimaro Dempo
  • Michio Mori
  • Jun-ichi Uchino
  • Hiroshi Kobayashi

Abstract

Two strains of Long-Evans rats, LEC and LEA were separated according to their coat colors. Acute hepatitis tends to occur spontaneously in the LEC rats after the 24th generation. As has been previously reported [1–3], the clinical course of the disease and the histopathological features closely resemble human fulminant hepatitis.

Keywords

Hepatitis Virus Acute Hepatitis Liver Homogenate Triamcinolone Acetonide Mouse Hepatitis Virus 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Tokyo 1991

Authors and Affiliations

  • Tsutomu Namieno
    • 1
    • 2
  • Noritoshi Takeichi
    • 1
  • Motomichi Sasaki
    • 3
  • Kimimaro Dempo
    • 4
  • Michio Mori
    • 4
  • Jun-ichi Uchino
    • 2
  • Hiroshi Kobayashi
    • 1
  1. 1.Laboratory of PathologyCancer InstituteJapan
  2. 2.First Department of Surgery, School of MedicineHokkaido UniversitySapporo, 060Japan
  3. 3.Sasaki Cancer InstituteChiyoda-ku, Tokyo, 101Japan
  4. 4.Department of PathologySapporo Medical CollegeSapporo, 060Japan

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