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Chromosomal Analysis of Spontaneous Hepatomas, a Derived Cell Line, and Chemically Induced Hepatomas in LEC Rats

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The LEC Rat

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Abstract

Recent banding studies of chromosomes in a variety of human and animal tumors have provided a growing body of evidence that certain specific or nonrandom chromosomal changes are causally related to or closely associated with the inhibition, promotion, or progression of malignant neoplasia [1–5]. Despite the vast amount of data now available on nonrandom occurrence of chromosomal abnormalities in human tumors, our knowledge on animal tumors appears to be very limited and the data on hand are rather conflicting.

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Author information

Authors and Affiliations

  1. Chromosome Research Unit, Faculty of Science, Hokkaido University, Sapporo, 060, Japan

    Michihiro C. Yoshida

  2. Sasaki Cancer Institute, Chiyoda-ku, Tokyo, 101, Japan

    Motomichi Sasaki

Authors
  1. Ryuichi Masuda
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  2. Takao Ono
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  3. Michihiro C. Yoshida
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  4. Motomichi Sasaki
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Editor information

Editors and Affiliations

  1. Department of Pathology, Sapporo Medical College, Minami 1, Nishi 17, Chuo-ku, Sapporo, 060, Japan

    Michio Mori M.D., Ph.D.

  2. Chromosome Research Unit, Faculty of Science, Hokkaido University, Kita 10, Nishi 8, Kita-ku Sapporo, 060, Japan

    Michihiro C. Yoshida D.Si., Ph.D.

  3. Laboratory of Pathology, Cancer Institute, Hokkaido University School of Medicine, Kita 15, Nishi 7, Kita-ku, Sapporo, 060, Japan

    Noritoshi Takeichi M.D., Ph.D.

  4. Department of Biochemistry, Osaka University Medical School, 2–2 Yamadaoka, Suita, Osaka, 565, Japan

    Naoyuki Taniguchi M.D., Ph.D.

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© 1991 Springer-Verlag Tokyo

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Masuda, R., Ono, T., Yoshida, M.C., Sasaki, M. (1991). Chromosomal Analysis of Spontaneous Hepatomas, a Derived Cell Line, and Chemically Induced Hepatomas in LEC Rats. In: Mori, M., Yoshida, M.C., Takeichi, N., Taniguchi, N. (eds) The LEC Rat. Springer, Tokyo. https://doi.org/10.1007/978-4-431-68153-3_27

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  • DOI: https://doi.org/10.1007/978-4-431-68153-3_27

  • Publisher Name: Springer, Tokyo

  • Print ISBN: 978-4-431-68155-7

  • Online ISBN: 978-4-431-68153-3

  • eBook Packages: Springer Book Archive

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