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The LEC Rat pp 196-208 | Cite as

Combined Immunodeficiency in LEC Rats with Spontaneous Hepatitis

  • Tsutomu Namieno
  • Noritoshi Takeichi
  • Motomichi Sasaki
  • Kimimaro Dempo
  • Michio Mori
  • Jun-ichi Uchino
  • Hiroshi Kobayashi

Abstract

One of the abnormalities in the LEC rat is immunoglobulin G (IgG) formation, and a definite correlation has been found between suppressed IgG formation and the incidence of hepatitis [1, 2]. Therefore, we investigated both cellular and humoral immunological competence in relation to the incidence of hepatitis.

Keywords

Spleen Cell Fulminant Hepatitis Natural Killer Activity Cytostatic Activity Blastogenic Response 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

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    Namieno T, Takeichi N, Sasaki M, Dempo K, Mori M, Uchino J, Kobayashi H (to be published) Pathogenesis of spontanteous hepatitis in Long-Evans Cinnamon (LEG) rats.Google Scholar
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Copyright information

© Springer-Verlag Tokyo 1991

Authors and Affiliations

  • Tsutomu Namieno
    • 1
    • 2
  • Noritoshi Takeichi
    • 2
  • Motomichi Sasaki
    • 3
  • Kimimaro Dempo
    • 4
  • Michio Mori
    • 4
  • Jun-ichi Uchino
    • 2
  • Hiroshi Kobayashi
    • 1
  1. 1.Laboratory of Pathology, Cancer InstituteHokkaido UniversitySapporo, 060Japan
  2. 2.First Department of Surgery, School of MedicineHokkaido UniversitySapporo, 060Japan
  3. 3.Sasaki Cancer InstituteChiyoda-ku, Tokyo, 101Japan
  4. 4.Department of PathologySapporo Medical CollegeSapporo, 060Japan

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