Skip to main content
SpringerLink
Log in

Combined Immunodeficiency in LEC Rats with Spontaneous Hepatitis

  • Chapter
The LEC Rat

Abstract

One of the abnormalities in the LEC rat is immunoglobulin G (IgG) formation, and a definite correlation has been found between suppressed IgG formation and the incidence of hepatitis [1, 2]. Therefore, we investigated both cellular and humoral immunological competence in relation to the incidence of hepatitis.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 39.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Namieno T, Takeichi N, Sasaki M, Dempo K, Mori M, Uchino J, Kobayashi H (to be published) Clinical and pathological characteristics of Long-Evans Cinnamon (LEC) rats with spontaneous development of hepatitis.

    Google Scholar 

  2. Namieno T, Takeichi N, Sasaki M, Dempo K, Mori M, Uchino J, Kobayashi H (to be published) Pathogenesis of spontanteous hepatitis in Long-Evans Cinnamon (LEG) rats.

    Google Scholar 

  3. Almeida JD, Waterson AP (1969) Immune complexes in hepatitis. Lancet II: 983–986.

    Article  Google Scholar 

  4. Dudley FJ, Fox RA, Sherlock S (1972) Cellular immunity and hepatitis-associated Australia antigen liver disease. Lancet I:723–726.

    Article  Google Scholar 

  5. Singh NK, Goyal AK, Srivastava PK, Gupta RM, Tripathi KK (1984) Immunological status in acute viral hepatitis and fulminant hepatic failure. J Indian Med Assoc 82:281–283.

    PubMed  CAS  Google Scholar 

  6. Tsutsui H, Mizoguchi Y, Yamamoto S, Morisawa S (1986) Studies on experimentally-induced acute hepatic failure: Possible involvement of activated liver adherent cells. In: Kirn A, Knook DL, Wisse E (eds) Cells of hepatic sinusoid. The Kupffer Cell Foundation, The Netherlands, pp 307–314.

    Google Scholar 

  7. Chapes SK, Stezhen H (1983) Role of Corynebacterium parvum in the activation of peritoneal macrophages. II. Identification of distinguishable anti-tumor activities by macrophage subpopulation. Cell Immunol 76:49–57.

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Laboratory of Pathology, Cancer Institute, Hokkaido University, Sapporo, 060, Japan

    Tsutomu Namieno & Hiroshi Kobayashi

  2. First Department of Surgery, School of Medicine, Hokkaido University, Sapporo, 060, Japan

    Tsutomu Namieno, Noritoshi Takeichi & Jun-ichi Uchino

  3. Sasaki Cancer Institute, Chiyoda-ku, Tokyo, 101, Japan

    Motomichi Sasaki

  4. Department of Pathology, Sapporo Medical College, Sapporo, 060, Japan

    Kimimaro Dempo & Michio Mori

Authors
  1. Tsutomu Namieno
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Noritoshi Takeichi
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Motomichi Sasaki
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Kimimaro Dempo
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Michio Mori
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Jun-ichi Uchino
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. Hiroshi Kobayashi
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Department of Pathology, Sapporo Medical College, Minami 1, Nishi 17, Chuo-ku, Sapporo, 060, Japan

    Michio Mori M.D., Ph.D.

  2. Chromosome Research Unit, Faculty of Science, Hokkaido University, Kita 10, Nishi 8, Kita-ku Sapporo, 060, Japan

    Michihiro C. Yoshida D.Si., Ph.D.

  3. Laboratory of Pathology, Cancer Institute, Hokkaido University School of Medicine, Kita 15, Nishi 7, Kita-ku, Sapporo, 060, Japan

    Noritoshi Takeichi M.D., Ph.D.

  4. Department of Biochemistry, Osaka University Medical School, 2–2 Yamadaoka, Suita, Osaka, 565, Japan

    Naoyuki Taniguchi M.D., Ph.D.

Rights and permissions

Reprints and permissions

Copyright information

© 1991 Springer-Verlag Tokyo

About this chapter

Cite this chapter

Namieno, T. et al. (1991). Combined Immunodeficiency in LEC Rats with Spontaneous Hepatitis. In: Mori, M., Yoshida, M.C., Takeichi, N., Taniguchi, N. (eds) The LEC Rat. Springer, Tokyo. https://doi.org/10.1007/978-4-431-68153-3_22

Download citation

  • DOI: https://doi.org/10.1007/978-4-431-68153-3_22

  • Publisher Name: Springer, Tokyo

  • Print ISBN: 978-4-431-68155-7

  • Online ISBN: 978-4-431-68153-3

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation