The LEC Rat pp 142-148 | Cite as

Differential Expression of Mn- and Cu,Zn-Superoxide Dismutases in Various Tissues of LEC Rats

  • Keiichiro Suzuki
  • Toshiyuki Nakata
  • Han Geuk Seo
  • Nobuko Miyazawa
  • Toshihiro Sugiyama
  • Naoyuki Taniguchi


Oxy-radicals are thought to play important roles in the course of multistep carcinogenesis [1–3]. Accurate detection of oxy-radicals is impossible, however, because of their instability and short half-life. Therefore, evaluation of the levels of enzymes involved in the metabolism of oxy-radicals appears to be the most reliable means of assessing oxy-radical metabolism in vivo.


Manganese Superoxide Dismutase Multistep Carcinogenesis Mitochondrial Manganese Superoxide Dismutase Metabolic Predisposition Immunoreactive SODs 
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Copyright information

© Springer-Verlag Tokyo 1991

Authors and Affiliations

  • Keiichiro Suzuki
  • Toshiyuki Nakata
  • Han Geuk Seo
  • Nobuko Miyazawa
  • Toshihiro Sugiyama
  • Naoyuki Taniguchi
    • 1
  1. 1.Department of BiochemistryOsaka University Medical SchoolSuita, Osaka, 565Japan

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