Abstract
Cis-diamminedichloroplatinum (CDDP) is known to be an effective drug against many malignant tumors [1,2]. However, in brain tumors, its usefulness is limited because of the blood-brain barrier [3]. To solve this problem, we are investigating the drug delivery system with liposome [4,5]. We have already reported liposome containing CDDP (Lip-CDDP) to be more useful than free-CDDP as a targeting therapy for brain tumors when we studied organ CDDP distribution using 9L-glioma implanted rats [5].
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References
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© 1991 Springer-Verlag Tokyo
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Ryu, N., Shibata, S., Ochi, A., Mori, K. (1991). Effects of CDDP on a Monolayer Cultured 9 L Glioma Cell Line—Evaluation by a FCM Study of a Cellular DNA Histogram. In: Tabuchi, K. (eds) Biological Aspects of Brain Tumors. Springer, Tokyo. https://doi.org/10.1007/978-4-431-68150-2_68
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DOI: https://doi.org/10.1007/978-4-431-68150-2_68
Publisher Name: Springer, Tokyo
Print ISBN: 978-4-431-68152-6
Online ISBN: 978-4-431-68150-2
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