Biological Characterization of Human Medulloblastoma (ONS-76 and ONS-81) Cell Lines

  • Keiji Shimizu
  • Masanobu Yamada
  • Syusuke Moriuchi
  • Kazuyoshi Tamura
  • Eiichiro Mabuchi
  • Yutaka Okamoto
  • Yasuyoshi Miyao
  • Kae Chang Park
  • Toru Hayakawa


Medulloblastomas are the most common malignant brain tumors in children. The origins of medulloblastoma cells are controversial. Most neuropathologists believe them to have originated from immature precursor cells which have the potentiality to differentiate into either neuronal or glial cells [1]. Although it is very difficult to establish a cell line of human medulloblastoma [2,3], we have established 2 cell lines with neuronal characteristics.


Major Histocompatibility Complex Glial Fibrillary Acidic Protein Medulloblastoma Cell Major Histocompatibility Complex Antigen Medulloblastoma Cell Line 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag Tokyo 1991

Authors and Affiliations

  • Keiji Shimizu
  • Masanobu Yamada
  • Syusuke Moriuchi
  • Kazuyoshi Tamura
  • Eiichiro Mabuchi
  • Yutaka Okamoto
  • Yasuyoshi Miyao
  • Kae Chang Park
  • Toru Hayakawa
    • 1
  1. 1.Department of NeurosurgeryOsaka University Medical SchoolOsaka, 553Japan

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