Expression of Intermediate Filaments (GFAP and Vimentin) in Human Gliomas

  • Takashi Kokunai
  • Norihiko Tamaki
  • Satoshi Matsumoto


Glial fibrillary acidic protein (GFAP) is expressed in developing, normal, reactive, and neoplastic glial cells [1,2]. In contrast to GFAP, vimentin, first detected in fibroblasts, characterizes the mesenchymal origin of the cells [3]. In addition to the expression of vimentin in mesenchymal cells, vimentin is thought to be a major cytoskeletal component of immature glias [3], and is expressed on some glial tumors [4].


Glial Fibrillary Acidic Protein Intermediate Filament Anaplastic Astrocytoma Glial Tumor Sodium Dodecyl Sulfate Concentration 
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Copyright information

© Springer-Verlag Tokyo 1991

Authors and Affiliations

  • Takashi Kokunai
  • Norihiko Tamaki
  • Satoshi Matsumoto
    • 1
  1. 1.Department of NeurosurgeryKobe University School of MedicineKobe, 650Japan

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