Allele Loss on Chromosome 10 in Human Glioblastomas
Recently, specific chromosomal deletions have been reported to be associated with many human malignancies. It is now thought that loss of constant genetic loci can be taken as evidence of recessive tumor suppressor genes involved in the genesis of human cancers. In this report, allelic deletions on chromosome 10 were studied in human malignant gliomas by using restriction fragment length polymorphisms (RFLPs) analyisis.
KeywordsAnaplastic Astrocytoma Allelic Deletion Human Glioblastoma Multiforme Specific Chromosomal Abnormality Human Malignant Astrocytoma
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