Malignancy of Glioma Estimated by PET-18F-FDG, PET-11C-Methionine, and SPECT-201Thallium
The detection of malignancy in glioma by histological studies and by the bromodeoxyuridine labeling index (BUdR-LI) have been well documented . Increased glucose and amino acid uptake in glioma measured by positron emission tomography (PET) with fluorine-18-fluorodeoxyglucose (FDG)  and with carbon-11-methionine (Met)  have been reported capable of identifying the malignant grade of lesions. Single photon emission CT (SPECT) with 201-thalium chloride (Tl) is also valuable for determining the grade of malignancy . A method of predicting malignancy preoperatively could alert the operating surgeon to the extent of tumor removal that will be required.
KeywordsPositron Emission Tomography Malignant Glioma Tumor Region Medial Temporal Lobe Pilocytic Astrocytoma
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