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Malignancy of Glioma Estimated by PET-18F-FDG, PET-11C-Methionine, and SPECT-201Thallium

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Abstract

The detection of malignancy in glioma by histological studies and by the bromodeoxyuridine labeling index (BUdR-LI) have been well documented [1]. Increased glucose and amino acid uptake in glioma measured by positron emission tomography (PET) with fluorine-18-fluorodeoxyglucose (FDG) [2] and with carbon-11-methionine (Met) [3] have been reported capable of identifying the malignant grade of lesions. Single photon emission CT (SPECT) with 201-thalium chloride (Tl) is also valuable for determining the grade of malignancy [4]. A method of predicting malignancy preoperatively could alert the operating surgeon to the extent of tumor removal that will be required.

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References

  1. Hoshino T, Nagashima T, Murovic JA, Wilson CB, Edwards MSB, Gutin PH, Davis RL, DeArmond SJ (1986) In situ cell kinetics studies on human neuroectodermal tumors with bromodeoxyuridine labeling. J Neurosurg 64: 453–459

    Article  PubMed  CAS  Google Scholar 

  2. Di Chiro G, DeLaPaz RL, Brooks RA, Sokoloff L, Kornblith PL, Smith BH, Patronas NJ, Kufta CV, Kessler RM, Johnston GS, Manning RG, Wolf AP (1982) Glucose utilization of cerebral gliomas measured by [18F] fluorodeoxyglucose and positron emission tomography. Neurology 32: 1323–1329

    PubMed  Google Scholar 

  3. Ericson K, Lilja A, Bergstrom M, Collins VP, Eriksson L, Ehrin E, von Hoist H, Lundqvist H, Langstrom B, Mosskin M (1985) Positron emission tomography with ([nC]methyl)-L-methionine, [11C] D-glucose, and [68Ga] EDTA in supratentorial tumors. J Comput Assist Tomogr 9: 683–689

    Article  PubMed  CAS  Google Scholar 

  4. Black KL, Hawkins RA, Kim KT, Becker DP, Lerner C, Marciano D (1989) Use of thalium-201 SPECT to quantitate malignancy grade of gliomas. J Neurosurg 71: 342–346

    Article  PubMed  CAS  Google Scholar 

  5. Araki Y, Imano Y, Hirata T, Andoh T, Sakai N, Yamada H (1989) Thalium-201 imaging of brain tumors using single photon emission CT (in Japanese). Kaku Igaku (Jpn J Nucl Med) 26: 1363–1369

    CAS  Google Scholar 

  6. Shishido F, Uemura K, Inugami A, Tomura N, Higano S, Fujita H, Murakami M, Kanno I, Yasui N, Mineura K (1990) Value of 11C-methionine and PET in the diagnosis of low-grade gliomas (in Japanese). Kaku Igaku (Jpn J Nucl Med) 27: 239–302.

    Google Scholar 

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© 1991 Springer-Verlag Tokyo

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Tamura, M., Shibasaki, T., Horikoshi, S., Oriuchi, N. (1991). Malignancy of Glioma Estimated by PET-18F-FDG, PET-11C-Methionine, and SPECT-201Thallium. In: Tabuchi, K. (eds) Biological Aspects of Brain Tumors. Springer, Tokyo. https://doi.org/10.1007/978-4-431-68150-2_18

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  • DOI: https://doi.org/10.1007/978-4-431-68150-2_18

  • Publisher Name: Springer, Tokyo

  • Print ISBN: 978-4-431-68152-6

  • Online ISBN: 978-4-431-68150-2

  • eBook Packages: Springer Book Archive

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