Abstract
Brain tumors are considered to have well-integrated metabolic systems, because each tumor survives and maintains an adenosine triphosphate (ATP) level and energy charge. Diversity of metabolic patterns was noted in specimens of human brain tumors [1]. Biochemical assay may not always reflect in vivo enzyme activities and the metabolites of resected tumor tissues: it is not pure and is usually contaminated with heterogenous materials such as necroses and stromal tissues.
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References
Lowry OH, Berger SJ, Carter JG, Chi MMY, Manchester JK, Knor J, Pusateri ME (1983) Diversity of metabolic patterns in human brain tumors: enzymes of energy metabolism and related metabolites and cofactors. J neurochem 41: 994–1010
Mineura K, Yasuda T, Kowada T, Shishido T, Ogawa T, Uemura K (1986) Positron emission tomographic evaluation of histological malignancy in gliomas using oxygen- 15 and fluorine-18-fluorodeoxyglucose. Neurol Res 8: 164–168
Mineura K, Kowada M, Shishido F (1989) Brain tumor imaging with synthesized 18F-fluorophenylalanine and positron emission tomography. Surg Neurol 31: 468–469
Mineura K, Sasajima T, Suda Y, Kowada M, Shishido F, Uemura K (1989) Early and accurate detection of primary cerebral glioma with interfibrillary growth using 11C-L-methionine positron emission tomography. J Med Imag 3: 192–196
Mineura K, Sasajima T, Suda Y, Kowada M, Shishido F, Uemura K (1990) Amino acids study of cerebral gliomas using positron emission tomography: Analysis of (11C-methyl)-L-methionine uptake index. Neurol Med Chir (Tokyo) 30: 997–1002
Mineura K, Sasajima T, Kowada M, Uesaka Y, Shishido F (1991) Innovative approach in the diagnosis of gliomatosis cerebri using 11C-L-methionine positron emission tomography. J Nucl Med 32: 726–728
DiChiro G, DeLaPaz RL, Brooks RA, Sokoloff L, Kornblith PL, Smith BH, Patronas NJ, Kufta CV, Kessler RM, Johnston GS, Manning RG, Wolf AP (1982) Glucose utilization of cerebral gliomas measured by [18F]fluorodeoxyglucose and positron emission tomography. Neurology 32: 1323–1329
Alavi JB, Alavi A, Chawluk J, Kushner M, Powe J, Hickey W, Reivich M (1988) Positron emission tomography in patients with glioma. A predictor of prognosis. Cancer 62: 1074–1078
Patronas NJ, DiChiro G, Kufta C, Bairamian D, Kornblith PL, Simon R, Larson SM (1985) Prediction of survival in glioma patients by means of positron emission tomography. J Neurosurg 62: 816–822
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© 1991 Springer-Verlag Tokyo
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Mineura, K., Sasajima, T., Kowada, M., Shishido, F., Uemura, K. (1991). PET Measurement of Tumor Metabolism in Patients with Gliomas. In: Tabuchi, K. (eds) Biological Aspects of Brain Tumors. Springer, Tokyo. https://doi.org/10.1007/978-4-431-68150-2_17
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DOI: https://doi.org/10.1007/978-4-431-68150-2_17
Publisher Name: Springer, Tokyo
Print ISBN: 978-4-431-68152-6
Online ISBN: 978-4-431-68150-2
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