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The Proliferative Potential After Hyperthermia and Irradiation on a Human Glioma Cell Line

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Biological Aspects of Brain Tumors

Abstract

The lethal effects of hyperthermia and irradiation on glioma cells have been demonstrated both in vitro and in vivo. In general, cells in the S-phase are the most resistant to X-rays, whereas they are the most sensitive to hyperthermia. In this report, the effect of hyperthermia or irradiation on cultured glioma cells was examined by colony formation assay. The effect of these treatments on the proliferative potential of the glioma cells was investigated with an immunohistochemical technique using monoclonalantibody (MoAb) against bromodeoxyuridine (BrdU) and MoAb Ki-67.

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© 1991 Springer-Verlag Tokyo

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Shigematsu, H. et al. (1991). The Proliferative Potential After Hyperthermia and Irradiation on a Human Glioma Cell Line. In: Tabuchi, K. (eds) Biological Aspects of Brain Tumors. Springer, Tokyo. https://doi.org/10.1007/978-4-431-68150-2_16

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  • DOI: https://doi.org/10.1007/978-4-431-68150-2_16

  • Publisher Name: Springer, Tokyo

  • Print ISBN: 978-4-431-68152-6

  • Online ISBN: 978-4-431-68150-2

  • eBook Packages: Springer Book Archive

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