Skip to main content

Rapid Assessment of Malignancy in Human Brain Tumors on Squash Preparations Using Nucleolar Organizer Region Staining

  • Chapter
  • 80 Accesses

Abstract

The intraoperative histologic diagnosis on conventional rapid frozen sections is very helpful in deciding the area to be resected during the operation of a brain tumor. However, the inadequately conserved construction of frozen tissues sometimes makes the histological diagnosis difficult. Therefore, the development of new convenient methods that can assist the rapid diagnosis of brain tumors and the estimation of their proliferative potential, even during surgery, is needed.

This is a preview of subscription content, log in via an institution.

Buying options

Chapter
USD   29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD   39.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD   54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD   54.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Learn about institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Crocker J, Nar P (1987) Nucleolar organizer regions in lymphomas. J Pathol 151: 111–118

    Article  PubMed  CAS  Google Scholar 

  2. Hall PA, Levison DA (1990) Review: Assessment of cell proliferation in histological material. J Clin Pathol 43: 184–193

    Article  PubMed  CAS  Google Scholar 

  3. Williams MA, Kleinschmidt JA, Krohne G, et al. (1982) Argyrophilic nuclear and nucleolar proteins of Xenopus laevis oocytes identified by gel electrophoresis. Exp Cell Res 137: 341–351

    Article  PubMed  CAS  Google Scholar 

  4. Ochs RL, Busch H (1984) Further evidence that phosphoprotein C23 (UOkD/ pH5.1) is in nucleolar silver staining protein. Exp Cell Res 152: 260–265

    Article  PubMed  CAS  Google Scholar 

  5. Lische MA, Smetana K, Olson MOJ, et al. (1984) Protein C23 and B23 are the major nucleolar silver staining proteins. Life Sci 25: 701–708

    Article  Google Scholar 

  6. Hara A, Hirayama H, Sakai N, et al. (1990) Correlation between nucleolar or-ganizer region staining and Ki-67 immunostaining in human gliomas. Surg Neurol 33: 320–324

    Article  PubMed  CAS  Google Scholar 

  7. Hara A, Hirayama H, Sakai N, et al. (1991) Nucleolar organizer region scores and Ki-67 labeling index in high-grade gliomas and metastatic brain tumors. Acta Neurochir (Wien) 109: 37–41

    Article  CAS  Google Scholar 

  8. Kajiwara K, Nishizaki T, Orita T, et al. (1990) Silver colloid technique for analysis of glioma malignancy. J Neurosurg 73: 113–117

    Article  PubMed  CAS  Google Scholar 

  9. Burger PC, Shibata T, Kleihues P (1986) The use of the monoclonal antibody Ki-67 in the identification of proliferating cells. Am J Surg Pathol 10: 611–617

    Article  PubMed  CAS  Google Scholar 

  10. Ostertag CB, Volk B, Shibata T, et al. (1987) The monoclonal antibody Ki-67 as a marker for proliferating cells in stereotactic biopsies of brain tumors. Acta Neurochir (Wien) 89: 117–121

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1991 Springer-Verlag Tokyo

About this chapter

Cite this chapter

Hara, A. et al. (1991). Rapid Assessment of Malignancy in Human Brain Tumors on Squash Preparations Using Nucleolar Organizer Region Staining. In: Tabuchi, K. (eds) Biological Aspects of Brain Tumors. Springer, Tokyo. https://doi.org/10.1007/978-4-431-68150-2_12

Download citation

  • DOI: https://doi.org/10.1007/978-4-431-68150-2_12

  • Publisher Name: Springer, Tokyo

  • Print ISBN: 978-4-431-68152-6

  • Online ISBN: 978-4-431-68150-2

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics