An Introduction to Molecular Biology for the Neuro-Oncologist

  • Mark A. Israel


There is now overwhelming evidence that cancer is a genetic disease resulting from alterations in DNA. Over the past decade, advances in molecular biology and recombinant DNA technology have permitted us to make great strides in the understanding of cancer. The powerful genetic tools provided by these experimental approaches have made it possible to identify chemical and biological alterations that occur during the transformation of normal cells to malignant ones, and to catalogue the cellular changes resulting from these alterations. Molecular approaches to the pathologic classification of tumors should soon provide a rational basis upon which novel therapeutic possibilities can be examined.


Epidermal Growth Factor Receptor Epidermal Growth Factor Receptor Gene Glial Tumor Human Brain Tumor Human Glioblastoma Cell Line 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag Tokyo 1991

Authors and Affiliations

  • Mark A. Israel
    • 1
  1. 1.Preuss Laboratory for Molecular Neuro-Oncology, Brain Tumor Research Center, Department of Neurological Surgery, School of MedicineUniversity of CaliforniaSan FranciscoUSA

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