Abstract
The cell and the extracellular matrix have some protective mechanisms against mineralization and body fluids contain widely varying macromolecules that inhibit mineralization. The precipitation of inorganic crystals from body fluid requires: (A)the elimination of the macromolecules inhibitory for crystal formation, (B)sufficient supersaturation of the relevant ions and (C)local restriction of molecular movement. All of these requirements must be performed in a several nano-meter space. In order to accomodate these requirements, the author proposes the “Nanospace Theory” for biomineralization in which extremely thin crystallites are formed in the ultramicrospace at the very beginning of mineralization[l,2]. Only hydroxyapatite mineralization will be discussed here.
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© 1991 Springer-Verlag Tokyo
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Katsura, N. (1991). Nanospace Theory for Biomineralization. In: Suga, S., Nakahara, H. (eds) Mechanisms and Phylogeny of Mineralization in Biological Systems. Springer, Tokyo. https://doi.org/10.1007/978-4-431-68132-8_32
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DOI: https://doi.org/10.1007/978-4-431-68132-8_32
Publisher Name: Springer, Tokyo
Print ISBN: 978-4-431-68134-2
Online ISBN: 978-4-431-68132-8
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