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Cardiac transplantation in the United States of America

  • Lawrence H. Cohn
  • Gilbert H. Mudge
Conference paper

Summary

Cardiac transplantation in the United States began with the experimental work by Shumway and Lower at Stanford and culminated in the performance of clinical heart transplantation at Stanford beginning in 1968 and continuing to the present. The numbers of centers in the United States have increased significantly since the general use of cyclosporin therapy began in 1984. The number of centers have increased from 35 in 1984 to over 150 in 1990. With this increase has come a decreasing number of donor hearts available per center and the number of transplants has leveled out at about 1700 per year. The number of donors has not increased substantially in the last several years as well.

The Brigham and Women’s Hospital began cardiac transplantation in 1984, and has performed 107 transplants to January 1990. The one-year survival rate is 85% and the five-year survival rate is approximately 70%.

Cardiac transplantation in the United States is a well- established procedure but the number of centers performing transplantation has escalated to the point that there is dilution of effort, both clinically and experimentally.

Keywords

Heart Transplantation Cardiac Transplantation Rejection Episode Donor Heart Severe Rejection 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Tokyo 1991

Authors and Affiliations

  • Lawrence H. Cohn
    • 1
  • Gilbert H. Mudge
    • 2
  1. 1.Harvard Medical School and Division of Cardiac SurgeryBrigham and Women’s HospitalBostonUSA
  2. 2.Harvard Medical School and Division of CardiologyBrigham and Women’s HospitalBostonUSA

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