Abstract
A 17 year old girl with chronic idiopathic pseudo-obstruction and short gut, had been on home parenteral nutrition for 17 months. Following diagnosis of severe selenium deficiency, she received intravenous supplemental selenium for the last seven months. She developed septic shock followed by cardiac arrest. At autopsy, the heart was enlarged, soft and flabby, and the histological findings were suggestive of cardiomyopathy due to prolonged selenium deficiency. Sepsis may precipitate cardiomyopathy in marginal selenium deficiency in a susceptible subject.
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References
Chen X,Yang G,Chen J et al (1980) Studies on the relations of selenium and Keshan Disease. Biol Tr Elem Res 2: 91–107
Collipp PJ.Chen SY (1981) Cardiomyopathy and Selenium Deficiency in a Two-Year-Old Girl. N Eng J Med 304: 1304–1305
Fleming CR,Lie JT, McCall JT et al (1982) Selenium Deficiency and Fatal Cardiomyopathy in a Patient on Home Parenteral Nutrition. Gastroenterology 83: 689–693
Johnson RA,Baker SS,Fallon JT et al (1981) An Occidental Case of Cardiomyopathy and Selenium Deficiency. New Eng J Med 304: 1210–1212
Levander OA,Morris VC (1984) Dietary selenium levels needed to maintain balance in North American adults consuming self-selected diets. Am J Clin Nutr 39: 809–815
McGovern VJ (1980) Hypovolemic shock with particular reference to the myocardial and pulmonary lesions. Pathology 12: 63–72
Quercia RA,Korn S, O’Neill D et al (1984) Selenium Deficiency and Fatal Cardiomyopathy in a Patient Receiving Long-term Home Parenteral Nutrition. Clin Pharmacol 3: 531–535
Sriram K,Peterson JK, O’Gara J, Hammond JM (1986) Clinical improvement of congestive heart failure after selenium supplementation in total parenteral nutrition. Acta Pharmacol Toxicol 59 (suppl VI I). 361–364
Stanley JC.Alexander JF,Nesbitt GA (1982) Selenium deficiency during total parenteral nutrition: a case report. Ulster Med J 51: 130–2
Van Rij AM,Thomson CD, McKenzie JM,Robinson MF (1979) Selenium deficiency in total parenteral nutrition. Am J Clin Nutr 32: 2076–85
Volk DM,Cutliff SA. (1986) Selenium Deficiency and Cardiomyopathy In a Patient With Cystic Fibrosis. J Kentucky Med Assoc 84: 222–224
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© 1990 Springer-Verlag Tokyo
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Lockitch, G., Dison, P., Taylor, G., Wong, L., Davidson, G., Riddell, D. (1990). Cardiomyopathy and Selenium Deficiency in a Caucasian Adolescent. In: Tomita, H. (eds) Trace Elements in Clinical Medicine. Springer, Tokyo. https://doi.org/10.1007/978-4-431-68120-5_32
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DOI: https://doi.org/10.1007/978-4-431-68120-5_32
Publisher Name: Springer, Tokyo
Print ISBN: 978-4-431-68122-9
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