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Platelet Glutathione Peroxidase Activity in Long-term Total Parenteral Nutrition with/without Selenium Supplementation

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Trace Elements in Clinical Medicine

Abstract

Platelet glutathione peroxidase (GSH-Px) activity in six patients receiving prolonged total parenteral nutrition (TPN) with chronic gastrointestinal diseases was studied to investigate its usefullness for an indicator of Se status. During Se depletion and repletion, blood Se indices were meaured. Platelet GSH-Px activity significantly decreased and increased in one week. Plasma Se indices significantly changed in three weeks. Erythrocyte Se indices showed no remarkable changes during study period. Platelet GSH-Px activity may be served as one of the most sensitive Se indices and useful for assessing the short-term Se status in TPN patients.

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Author information

Authors and Affiliations

  1. Department of Pediatric Surgery, Kure National Hospital, 3-1 Aoyama-cho, Kure, 737, Japan

    Kinya Sando

  2. Department of Pediatric Surgery, Osaka University Medical School, 1-1-50 Fukushima, Fukushima-ku, Osaka, 553, Japan

    Riichiro Nezu, Yoji Takagi & Akira Okada

Authors
  1. Kinya Sando
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  2. Riichiro Nezu
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  3. Yoji Takagi
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  4. Akira Okada
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Editor information

Editors and Affiliations

  1. Department of Otorhinolaryngology, Nihon University School of Medicine, 173, Ohyaguchi, Itabashi-ku Tokyo, Japan

    Hiroshi Tomita M.D. (Professor and Chairman) (Professor and Chairman)

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© 1990 Springer-Verlag Tokyo

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Sando, K., Nezu, R., Takagi, Y., Okada, A. (1990). Platelet Glutathione Peroxidase Activity in Long-term Total Parenteral Nutrition with/without Selenium Supplementation. In: Tomita, H. (eds) Trace Elements in Clinical Medicine. Springer, Tokyo. https://doi.org/10.1007/978-4-431-68120-5_31

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  • DOI: https://doi.org/10.1007/978-4-431-68120-5_31

  • Publisher Name: Springer, Tokyo

  • Print ISBN: 978-4-431-68122-9

  • Online ISBN: 978-4-431-68120-5

  • eBook Packages: Springer Book Archive

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