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Pathophysiological Significance of an Oral Zinc Tolerance Test in Patients with Chronic Hepatic Diseases

  • Yasuyuki Arakawa
  • Kazutomo Suzuki
  • Keiko Suzuki
  • Naohide Tanaka
  • Yutaka Matsuo
  • Shigeo Takeuchi
Conference paper

Abstract

The significances of the biochemical and nutritional roles of metals, particularly trace metals, is widely recognized because they are found in vivo as constituent components of many metalloproteins and metalloenzymes. In addition, a close correlation between trace metal metabolism and the pathology of hepatic diseases has been recognized based on the fact that such metalloproteins and metalloenzymes are synthesized and react mainly in the liver and trace metals such as iron, copper, zinc, magnesium and manganese act as cofactors against hepatic fibrosis in chronic hepatic diseases, particularly the biosynthesis of collagen.

Keywords

Liver Cirrhosis Primary Biliary Cirrhosis Chronic Active Hepatitis Serum Zinc Zinc Sulfate 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Tokyo 1990

Authors and Affiliations

  • Yasuyuki Arakawa
    • 1
    • 2
  • Kazutomo Suzuki
    • 1
    • 2
  • Keiko Suzuki
    • 1
    • 2
  • Naohide Tanaka
    • 1
    • 2
  • Yutaka Matsuo
    • 1
    • 2
  • Shigeo Takeuchi
    • 1
    • 2
  1. 1.Third Department of Internal MedicineNihon University School of MedicineItabashi-Ku, TokyoJapan
  2. 2.Department of ChemistryNihon University School of MedicineItabashi-Ku, TokyoJapan

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