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Transdermal Scopolamine in the Treatment of Vertiginous Episodes Associated with Ménière’s Disease

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Ménière’s Disease

Abstract

The parasympatholytic drugs, the antihistamines, and the phenothiazine tranquilizers all have a central depressant action and have long been used in preventing or treating motion sickness. The most widely used drugs are those with few atropine-like or sedative side-effects and thanks to the interest of the armed forces, many field studies and clinical trials evaluating drugs against motion sickness are available [1, 2]. In 1966, Brand and Perry [3] compiled exhaustive reviews on drugs used in motion sickness. They reported that there is no substitute for l-hyoscine (scopolamine) where the aim is to provide quick action but short-term protection against exposure to severe motion, but that for the prophylaxis of motion sickness during a long voyage, the diphenhydramine, cyclizine, may afford adequate protection.

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© 1990 Springer-Verlag Tokyo

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Kumoi, T., Inamori, T., Mori, H. (1990). Transdermal Scopolamine in the Treatment of Vertiginous Episodes Associated with Ménière’s Disease. In: Kitahara, M. (eds) Ménière’s Disease. Springer, Tokyo. https://doi.org/10.1007/978-4-431-68111-3_23

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  • DOI: https://doi.org/10.1007/978-4-431-68111-3_23

  • Publisher Name: Springer, Tokyo

  • Print ISBN: 978-4-431-68113-7

  • Online ISBN: 978-4-431-68111-3

  • eBook Packages: Springer Book Archive

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