The Treatment of Ménière’s Disease with Isosorbide

  • Hiroya Kitano
  • Masaaki Kitahara


It is widely accepted that endolymphatic hydrops is a common pathological feature of Ménière’s disease. Therefore, at present, the most logical and effective medical treatment for this ailment is believed to be with drugs which reduce hydrops. Isosorbide (ISO) has been shown to be effective for glaucoma and intracranial hypertension, the pathologies of which are similar to that of Ménière’s disease. In this paper, in order to determine the efficacy of ISO with regard to Ménière’s disease, we attempted, in cooperation with 14 other institutes, a double-blind crossover trial of ISO on Meniere’s disease.


Hearing Loss Utility Rating Global Improvement Rebound Phenomenon Endolymphatic Hydrops 
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Copyright information

© Springer-Verlag Tokyo 1990

Authors and Affiliations

  • Hiroya Kitano
  • Masaaki Kitahara

There are no affiliations available

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