Skip to main content

The Effect of Steroids on Endolymphatic Hydrops Induced by an Immunological Technique

  • Chapter
Book cover Ménière’s Disease
  • 99 Accesses

Abstract

Steroids are less frequently used for the treatment of Ménière’s disease compared with their use for sudden deafness or facial paresis. Hauser [1] reported 2 cases of Ménière’s disease in which hearing was improved by the administration of steroids. McCabe [2], Hughes et al. [3, 4] and Shea [5] also reported the efficacy of steroids in cases of sensorineural hearing loss and/or Ménière’s disease with a suspected immunological origin. According to our 1970 and 1980 nationwide surveys [6, 7], incidences where otolaryngologists treated Ménière’s disease with steroids increased from 2% to 7%. It is true that steroids are one of the few drugs which have promising effects on certain types of Ménière’s disease. This study was made to examine the effects of steroids on endolymphatic hydrops experimentally induced in guinea pigs by an immunological technique [8].

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Hauser E (1959) Ménière’s disease; a new therapeutic approach. J Am Geriatr Soc 7: 874–876

    Google Scholar 

  2. McCabe BF (1979) Autoimmune sensorineural hearing loss. Ann Otol Rhinol Laryngol 88: 585–589

    PubMed  CAS  Google Scholar 

  3. Hughes GB, Kinney SE, Barna BP, Calabrese LH (1983) Autoimmune reactivity in Ménière’s disease. A preliminary report. Laryngoscope 93: 410–417

    CAS  Google Scholar 

  4. Hughes GB, Barna BP, Kinney SE, Calabrese LH, Hamid MA, Nalepa NJ (1988) Autoimmune endolymphatic hydrops: five-year review. Otolaryngol Head Neck Surg 88: 221–225

    Google Scholar 

  5. Shea JJ (1983) Autoimmune sensorineural hearing loss as aggravating factor in Ménière’s disease. Adv Otorhinolaryngol 30: 254–257

    PubMed  CAS  Google Scholar 

  6. Yagi N, Kitahara M (1972) Treatment for Ménière’s disease (in Japanese). Pract Otol (Kyoto) 65: 923–930

    Google Scholar 

  7. Kitajima K, Saito H, Kitano H, Kitahara M (1981) The trend of treatment in Ménière’s disease during the past 10 years (in Japanese). Pract Otol (Kyoto) 74: 2396–2405

    Google Scholar 

  8. Sawada I, Kitahara M, Kitajima K, Yazawa Y (1987) Induction of experimental endolymphatic hydrops by immunologic technique. Am J Otol 8: 330–334

    PubMed  CAS  Google Scholar 

  9. Paparella MM, Goycoolea MV, Meyerhoff WL, Shea D (1979) Endolymphatic hydrops and otitis media. Laryngoscope 89: 43–54

    PubMed  CAS  Google Scholar 

  10. Kimura RS, Schuknecht HF (1965) Membranous hydrops in the inner ear of the guinea pig after obliteration of the endolymphatic sac. Pract Oto-rhino-larying 27: 343–354

    Google Scholar 

  11. Kimura RS (1985) Surgical and drug intervention in experimentally induced endolymphatic hydrops. In: Nomura Y (ed) Hearing and dizziness. Igaku-Shoin, Tokyo, p 16

    Google Scholar 

  12. Matsubara H (1981) Basic experiment of attacks of Ménière’s disease (in Japanese). Pract Otol (Kyoto) 74: 2418–2449

    Google Scholar 

  13. Kawase T, Kusakari J, Shinkawa H, Takasaka T (1988) Effect of perilymphatic pressure on the CM threshold in hydropic ears of guinea pigs (in Japanese). Equilibrium Res [Suppl] 4: 37–40

    Article  Google Scholar 

Download references

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1990 Springer-Verlag Tokyo

About this chapter

Cite this chapter

Yazawa, Y., Kitahara, M., Uchida, K., Sawada, I. (1990). The Effect of Steroids on Endolymphatic Hydrops Induced by an Immunological Technique. In: Kitahara, M. (eds) Ménière’s Disease. Springer, Tokyo. https://doi.org/10.1007/978-4-431-68111-3_10

Download citation

  • DOI: https://doi.org/10.1007/978-4-431-68111-3_10

  • Publisher Name: Springer, Tokyo

  • Print ISBN: 978-4-431-68113-7

  • Online ISBN: 978-4-431-68111-3

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics