Blood Pressure in Mesenteric Microvessels of Normotensive and Hypertensive Rats: Application of a Servo-Nulling Micropressure System
It is of physiological importance to measure directly the pressure in in vivo microvessels since this may reflect the hemodynamic nature in the microvascular network. A number of techniques have been proposed for the direct measurement of microvascular pressure, but a servo-nulling technique  has been commonly used because it can provide accurate information about the microhemodynamics. In fact, this method has made it possible to measure blood pressure at a particular point in the microvascular network and to measure unsteady micropressure because of its high-frequency response capability. According to various reports, the response frequency ranges from 0 to 20–60 Hz [1–4]. In this paper, applications of the servo-nulling method to the microvasculature of normotensive and hypertensive rats are investigated.
KeywordsCapillary Pressure Microvascular Network Glass Micropipette External Fluid Hydrostatic Pressure Gradient
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- 1.Wiederhielm CA, Woodbury JW, Kirk S, Rushmer RF (1963) Pulsatile pressures in the microcirculation offrog’s mesentery. Am J Physiol 207: H173-H176Google Scholar