Abstract
Many complications of diabetes mellitus are widely known, while the etiology is not as yet clearly understood. It is generally suspected that hemorheological alterations and microhemodynamic changes play major roles in the pathophysiological mechanism of diabetic microangiopathy. In an attempt to clarify the etiology of diabetic microangiopathy, diabetic subjects, boderline subjects, and normal subjects were examined with respect to microhemodynamic changes in the venules on the human bulbar conjunctiva and hemorheological changes in peripheral blood before and after performing a 75 g oral glucose tolerance test (75g-0GTT).
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Tsushima N, Satoh T, Koyama T (1981) Human microcirculation (MC) by intra-vital microsopic system (IVVMS). Bibltheca Anat 20: 716–719
Tsushima N, Nakayama R (1983) Microcirculation of bulbar conjunctiva. Excepta Medica ICS 625: 15–28
Kikuchi Y, Arai T, Koyama T (1983) Improvement filtration method for red cell deformability measurement. Med Bioi Eng Comput 21: 270–276
Pyke DA, Tattersall RB (1973) Diabetic retinopathy in identical twins. Diabetes 22: 613–618
Leslie RBG, Barnett AH, Pyke DA (1979) Chlorpropamide alcohol flushing and diabetic retinopathy. Lancet 1: 997–999
Stout RW (1979) Diabetes and atherosclerosis-The role of insulin. Diabetologica 16: 141–150
Stout RW (1968) Insulin stimulated lipogenesis in arterial tissue in relation to diabetes and atheroma. Lancet 2: 702–703
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© 1988 Springer-Verlag Tokyo
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Sakakura, M., Kaba, M., Tsushima, N. (1988). Microangiopathy in Diabetes Mellitus. In: Manabe, H., Zweifach, B.W., Messmer, K. (eds) Microcirculation in Circulatory Disorders. Springer, Tokyo. https://doi.org/10.1007/978-4-431-68078-9_54
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DOI: https://doi.org/10.1007/978-4-431-68078-9_54
Publisher Name: Springer, Tokyo
Print ISBN: 978-4-431-68080-2
Online ISBN: 978-4-431-68078-9
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