The Interaction of Immune Complexes in Microcirculatory Impairment in Patients with Vasculitis

  • Terence J. Ryan


Vasculitis is an inflammatory response as a consequence of injury to small vessels. However, a concept popular during the past decade is that vasculitis is an immunological response, but many factors other than immunological processes are responsible for the final pathology and clinical picture of vasculitis [1, 2]. The injury done to blood vessels produces changes in their perfusion, damage to the endothelium with exhaustion of many of its functions, leakiness so that materials of all kinds can finally escape into the tissues, and during the process of repair, angiogenesis gives rise to abnormal or changed vascular patterns [3].


Immune Complex Immunological Process Elastin Fibre Microvascular Injury Poor Perfusion 
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Copyright information

© Springer-Verlag Tokyo 1988

Authors and Affiliations

  • Terence J. Ryan
    • 1
  1. 1.Department of DermatologySlade HospitalHeadington, OxfordEngland

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