Microcirculatory Studies on Epidural Spinal Cord Electrical Stimulation in Patients with Severe Lower Limb Ischemia

  • Michael J. H. M. Jacobs
  • Paul J. G. Jörning
  • Soures R. Joshi
  • Dick W. Slaaf
  • Robert S. Reneman


The approach to treatment of patients with chronic occlusive arterial disease of the lower extremities depends on the severity and extent of the obstructive lesions. Arterial reconstructive surgery remains the therapy of choice, but in approximately 20% of patients with ulceration and gangrene, vascular surgery is not effective [1].


Spinal Cord Stimulation Microcirculatory Parameter Nutritional Blood Flow Epidural Electrical Stimulation Epidural Spinal Cord Stimulation 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    Gregg RO (1985) Bypass or amputation? Concomitant review of bypass arterial grafting and major amputations. Am J Surg 149: 397–402PubMedCrossRefGoogle Scholar
  2. 2.
    Long DM (1977) Electrical stimulation for the control of pain. Arch Surg 112: 884–888PubMedCrossRefGoogle Scholar
  3. 3.
    Cook AW, Oygar A, Baggenstos P, Pacheco S, Kleriga E (1976) Vascular disease of extremities. Electric stimulation of spinal cord and posterior roots. NY St J Med 76: 366–368Google Scholar
  4. 4.
    Jacobs MJHM, Breslau PJ, Slaaf DW, Reneman RS, Lemmens HAJ (1987) Nomenclature of Raynaud’s phenomenon. A capillary microscopic and hemorheologic study. Surgery 101 (2): 136–145PubMedGoogle Scholar
  5. 5.
    Augustinsson LE, Holm J, Carlsson CA, Jivegard L (1985) Epidural electrical stimulation in severe limb ischaemia. Evidence of pain relief, increased blood flow and a possible limb-saving effect. Ann Surg 202: 104–111PubMedCrossRefGoogle Scholar
  6. 6.
    Melzack R, Wall PD (1965) Pain mechanism: a new theory. Science 150: 971–979PubMedCrossRefGoogle Scholar
  7. 7.
    Hilton SM, Marshall JM (1980) Dorsal root vasodilatation in cat skeletal muscle. J Physiol 299: 277–288PubMedGoogle Scholar

Copyright information

© Springer-Verlag Tokyo 1988

Authors and Affiliations

  • Michael J. H. M. Jacobs
    • 1
  • Paul J. G. Jörning
    • 1
  • Soures R. Joshi
    • 2
  • Dick W. Slaaf
    • 3
  • Robert S. Reneman
    • 4
  1. 1.Departments of SurgeryUniversity of LimburgMaastrichtThe Netherlands
  2. 2.Departments of AnesthesiologyUniversity of LimburgMaastrichtThe Netherlands
  3. 3.Departments of BiophysicsUniversity of LimburgMaastrichtThe Netherlands
  4. 4.Departments of PhysiologyUniversity of LimburgMaastrichtThe Netherlands

Personalised recommendations