Flow Characteristics in Poststenotic Regions of the Human Coronary Artery Assessed by 20-MHz 80-Channel Pulsed Doppler Velocimetry

  • Fumihiko Kajiya
  • Yoshifumi Wada
  • Takashi Fujiwara


A detailed assessment of flow dynamics in coronary stenosis is essential for better understanding of the pathophysiology of the obstructive coronary artery disease. However, measurements of phasic blood flow velocity and velocity distribution in a native human coronary artery have been hampered by methodological limitations. The ultrasound pulsed Doppler method is useful for measuring local blood flow velocity in vessels noninvasively. However, a conventional single-channel pulsed Doppler velocimeter with low carrier frequencies cannot obtain detailed blood velocity profiles of small vessels like the coronary artery. Recently, we have developed an 80-channel 20-MHz pulsed Doppler velocimeter [1-3], which detects Doppler signals from 80 channels by a zero-cross method and analyzes Doppler signals from one optional channel by a fast Fourier transform method, both in real time.


Left Anterior Anterior Descend Blood Flow Velocity Human Coronary Artery Velocity Waveform Graft Occlusion 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    Ogasawara Y, Hiramatsu O, Kagiyama M, Tsujioka K, Tomonaga G, Kajiya F, Yanashima T, Kimura Y (1984) Evaluation of blood velocity profile by high frequency ultrasound pulsed Doppler velocimeter by a multigated zerocross method together with a Fourier transform method. IEEE Comput Cardiol 447Google Scholar
  2. 2.
    Kajiya F, Ogasawara Y, Tsujioka K, Nakai M, Goto M, Wada Y, Tadaoka S, Matsuoka D, Mito K, Fujiwara T (1986) Evaluation of human coronary blood flow with an 80 channel pulsed Doppler velocimeter and zero-cross and Fourier transform methods during cardiac surgery. Circulation 74 (suppl 3): 53Google Scholar
  3. 3.
    Kajiya F, Tsujioka K, Ogasawara Y, Wada Y, Matsuoka S, Kanazawa S, Hiramatsu O, Tadaoka S, Goto M, Fujiwara T (1987) Analysis of flow characteristics in poststenotic regions of the human coronary artery during bypass graft surgery. Circulation 76: 1092PubMedCrossRefGoogle Scholar
  4. 4.
    Marcus ML, Write CB, Doty DB, Eastham CL, Laughlin D, Krumm P, Fastenow C, Brody MJ (1981) Measurements of coronary velocity and reactive hyperemia in the coronary circulation of humans. Circ Res 49: 877PubMedGoogle Scholar
  5. 5.
    Hartley CJ, Cole JS (1974) An ultrasound pulsed Doppler system for measuring blood flow in small vessels. J Appl Physiol 37: 626PubMedGoogle Scholar
  6. 6.
    Young DF, Tsai FY (1973) Flow characteristics in models of arterial stenosis: I. Unsteady flow. J Biomech 6: 547PubMedCrossRefGoogle Scholar
  7. 7.
    Khalifa AMA, Giddens DP (1981) Characterization and evolution of poststenotic flow disturbances. J Biomech 14: 279PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag Tokyo 1988

Authors and Affiliations

  • Fumihiko Kajiya
    • 1
  • Yoshifumi Wada
    • 1
  • Takashi Fujiwara
    • 2
  1. 1.Department of Medical Engineering and Systems CardiologyKawasaki Medical SchoolKurashiki, OkayamaJapan
  2. 2.Department of Thoracic SurgeryKawasaki Medical SchoolKurashiki, OkayamaJapan

Personalised recommendations