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Bordering Zone Hyperemia and Glucose Metabolism in Experimental Cerebral Ischemia

  • Junichiro Choki
  • Yasuhiro Hasegawa
  • Kazuo Minematsu
  • Takenori Yamaguchi

Abstract

Areas of increased blood flow (hyperemia) at the periphery of ischemic foci have been noted in experimental animals [1]. Experiments using 14C-2-deoxyglucose (2-D G) for the measurement of local cerebral glucose utilization (LCGU) have also demonstrated increased uptake of 2-DG in the bordering zone of focal ischemia [2]. The present study was designed to elucidate the relationship between hyperemia and increased 2-DG uptake in gerbils with unilateral common carotid artery (CCA) occlusion.

Keywords

Common Carotid Artery Ischemic Focus Mongolian Gerbil Left Common Carotid Artery Local Cerebral Blood Flow 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

References

  1. 1.
    Blair RD, Waltz AG (1970) Regional cerebral blood flow during acute ischemia. Correlation of autoradiographic measurements with observations of cortical microcirculation. Neurology 20: 802–808PubMedGoogle Scholar
  2. 2.
    Welsh FA, Greenberg JH, Jones SC, Ginsberg MD, Reivich M (1980) Correlation between glucose utilization and metabolic levels during focal ischemia in cat brain. Stroke 11: 79–84PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag Tokyo 1988

Authors and Affiliations

  • Junichiro Choki
    • 1
  • Yasuhiro Hasegawa
    • 1
  • Kazuo Minematsu
    • 2
  • Takenori Yamaguchi
    • 1
  1. 1.Cerebrovascular DivisionNational Cardiovascular CenterSuita, Osaka, 565Japan
  2. 2.Research InstituteNational Cardiovascular CenterSuita, Osaka, 565Japan

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