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Cerebral Hyperemia and Breakthrough During Hypertension

  • Seizo Sadoshima
  • Masatoshi Fujishima

Abstract

Cerebral blood flow is maintained relatively constant with variations of perfusion pressure. This autoregulatory function is adapted to higher levels of blood pressure in hypertensive humans and animals than in normotensives [1, 2]. The present study was designed to elucidate the effect of sympathetic denervation on the autoregulatory capacity in the cortex and thalamus during the development of hypertension.

Keywords

Cerebral Blood Flow Cerebral Autoregulation Sympathetic Denervation Rest Blood Pressure Pial Artery 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    Strandgaards S, Olesen J, Skinhoj E, Lassen NA (1973) Autoregulation of brain circulation in severe arterial hypertension. Br Med J 1: 507–510CrossRefGoogle Scholar
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    Vinall PE, Simenone FA (1981) Cerebral autoregulation. An in vitro study. Stroke 12: 640–642PubMedCrossRefGoogle Scholar
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    Sadoshima S, Yoshida F, Ibayashi S, Shiokawa O, Fujishima M (1985) Upper limit of cerebral autoregulation during development of hypertension in spontaneously hypertensive rats-Effect of sympathetic denervation. Stroke 16: 477–481PubMedCrossRefGoogle Scholar
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    Sadoshima S, Fujii K, Kusuda K, Shiokawa O, Yao Y, Ibayashi S, Fujishima M (1987) Importance of bilateral sympathetic innervation on cerebral blood flow autoregulation in the thalamus. Brain Res 413: 297–301PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag Tokyo 1988

Authors and Affiliations

  • Seizo Sadoshima
  • Masatoshi Fujishima
    • 1
  1. 1.Second Department of Internal MedicineKyushu University, School of MedicineHigashi-ku, Fukuoka City 812Japan

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