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Gastric Microvascular Effects of the Pro-ulcerogenic Mediator PAF-Acether

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Microcirculation in Circulatory Disorders

Abstract

Platelet-activating factor (PAF)-acether is an endogenous phospholipid that can be formed and released by a variety of cell types, including platelets, neutrophils, basophils, macrophages, monocytes and endothelial cells [1]. Its immediate precursor, lyso-PAF, is released from membrane-bound phospholipids by the action of phospholipase A2, the enzyme which also releases arachidonic acid.

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© 1988 Springer-Verlag Tokyo

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Whittle, B.J.R., Esplugues, J.V., Guth, P.H. (1988). Gastric Microvascular Effects of the Pro-ulcerogenic Mediator PAF-Acether. In: Manabe, H., Zweifach, B.W., Messmer, K. (eds) Microcirculation in Circulatory Disorders. Springer, Tokyo. https://doi.org/10.1007/978-4-431-68078-9_19

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  • DOI: https://doi.org/10.1007/978-4-431-68078-9_19

  • Publisher Name: Springer, Tokyo

  • Print ISBN: 978-4-431-68080-2

  • Online ISBN: 978-4-431-68078-9

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