Dynamics of Left Ventricular Filling
The laws of physics indicate that transmitral filling patterns are uniquely determined by the impedance of the mitral apparatus and the atrioventricular pressure difference. This paper reviews the results of the simultaneous measurement of left atrial and ventricular pressures and mitral flow in the experimental laboratory. The data support the theory: the pressure difference is due to accelerative and dissipative forces. It is now important to determine how disease and stress acutely and chronically affect the properties of both the ventricle and the atrium. With this knowledge, we will be better able to relate the non-invasive measurement of transmitral filling patterns to the active and passive properties of both chambers of the left heart.
KeywordsMitral Valve Diastolic Function Heart Sound Ventricular Pressure Left Atrial Pressure
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