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Coupling Between Ventricluar and Arterial Properties

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Book cover Recent Progress in Failing Heart Syndrome

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Summary

The ventricle transfers the mechanical energy of contraction to blood accumulated in the ventricular chamber to provide adequate cardiac output for peripheral perfusion and to generate adequate pressure in the ascending aorta. The ventricle is generally considered matched to a given load if it allows a maximal amount of external work against that load, while the matching between the ventricle and arterial system can also be defined from the principle of economical fuel consumption or mechanical efficiency.

Ventriculo-arterial coupling will deviate from the optimal condition through changes in elastance of either ventricle or artery. Ventricular and arterial properties are substantially modified by aging, arteriosclerosis, and hypertension together with myocardial hypertrophy.

When the ventriculo-arterial coupling is investigated in humans in terms of end-systolic elastance of the ventricle and effective input elastance of the arterial tree, it is normally set toward higher left ventricular work efficiency, whereas in patients with moderate cardiac dysfunction, this coupling is adjusted to maximize stroke work at the expense of the work efficiency. Neither the stroke work nor the work efficiency is near maximum for patients with severe cardiac dysfunction.

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Authors and Affiliations

  1. The Second Department of Internal Medicine, Toyama Medical and Pharmaceutical University, Toyama, 930-01, Japan

    Shigetake Sasayama & Hidetsugu Asanoi

Authors
  1. Shigetake Sasayama
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  2. Hidetsugu Asanoi
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Editors and Affiliations

  1. The Second Department of Internal Medicine, Toyama Medical and Pharmaceutical University, 2630 Sugitani, 930-01, Toyama, Japan

    Shigetake Sasayama M.D. (Professor of Medicine) (Professor of Medicine)

  2. Okayama University Medical School, 2-5-1, Shikata-cho, 700, Okayama, Japan

    Hiroyuki Suga M.D., D.M. SC. (Professor of Physiology) (Professor of Physiology)

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© 1991 Springer-Verlag Tokyo

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Sasayama, S., Asanoi, H. (1991). Coupling Between Ventricluar and Arterial Properties. In: Sasayama, S., Suga, H. (eds) Recent Progress in Failing Heart Syndrome. Springer, Tokyo. https://doi.org/10.1007/978-4-431-67955-4_8

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  • DOI: https://doi.org/10.1007/978-4-431-67955-4_8

  • Publisher Name: Springer, Tokyo

  • Print ISBN: 978-4-431-68019-2

  • Online ISBN: 978-4-431-67955-4

  • eBook Packages: Springer Book Archive

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