Summary
We describe here a new method of defining regional work and regional contractility of the myocardium of the ventricular wall using the relationship between mean wall stress (σ) and the natural logarithm of reciprocal of wall thickness (ln(1/H)). Regional work of the ventricle normalized to a unit volume of myocardium is equal to the area surrounded by the loop described by the σ-ln(1/H) relation during a cardiac cycle. The constant kSM of the end systolic σ-ln(1/H) relation, σ = Cexp(kSM ln(1/H)), corresponds to the myocardial elastic stiffness constant, which is sensitive to changes in contractile state, insensitive to changes in loading conditions and independent of ventricular size.
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© 1991 Springer-Verlag Tokyo
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Sugawara, M., Nakano, K., Kawana, M., Umemura, J., Sasayama, S., Carabello, B.A. (1991). Regional Work of the Left Ventricle and Contractility Index Independent of Ventricular Size. In: Sasayama, S., Suga, H. (eds) Recent Progress in Failing Heart Syndrome. Springer, Tokyo. https://doi.org/10.1007/978-4-431-67955-4_11
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DOI: https://doi.org/10.1007/978-4-431-67955-4_11
Publisher Name: Springer, Tokyo
Print ISBN: 978-4-431-68019-2
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